Bronchial carcinoids
نویسندگان
چکیده
منابع مشابه
The cellular structure of bronchial carcinoids.
A histological and electronmicroscopic study of bronchial carcinoids indicated that these tumours are argyrophilic in keeping with their occurrence in tissue of embryologically foregut origin. Normal bronchi contain cells that resemble, in their electronmicroscopic content, intestinal Kultschitzky-type cells. Characteristic of the carcinoid cell is the presence of intracellular neurosecretory g...
متن کاملmTOR inhibition, a potential novel approach for bronchial carcinoids.
Although targeted therapy, including inhibitors of mammalian target of rapamycin (mTOR) and vascular endothelial growth factor, being developed for carcinoids arised from the gastrointestinal tract, treatment for locally advanced or metastatic bronchial carcinoids (BCs) remains lacking. Traditional cytotoxic chemotherapy offers essentially minimal benefit to this largely under-characterized tum...
متن کاملEverolimus as a new potential antiproliferative agent in aggressive human bronchial carcinoids.
Bronchial carcinoids (BCs) are rare tumors originating from endocrine cells dispersed in the respiratory epithelium. It has been previously demonstrated that everolimus, or RAD001, an mTOR inhibitor, has potent antiproliferative effects in human endocrine tumors. Our aim was to evaluate the possible antiproliferative effects of everolimus in human BCs in primary culture. We collected 24 BCs tha...
متن کاملLong-Term Follow-Up of Flexible Bronchoscopic Treatment for Bronchial Carcinoids with Curative Intent
Background. Typical pulmonary carcinoids represent less than 5% of primary lung tumors. In patients with typical bronchial carcinoid, formal surgical resection still remains the gold-standard treatment. Data regarding long-term outcome in using flexible bronchoscope-based modalities under conscious sedation is very limited. Objectives. We sought to investigate, over extended follow-up period, t...
متن کاملCarcinoids of the Intestinal Tract
CARCINOID or argentaffin tumours of the intestine have for a considerable time aroused the interest of pathologists, histologists, and others, and many papers on these peculiar growths have been added to the rapidly growing medical literature. These tumours occur mainly in the small intestine and appendix, which are sites rarely affected by other primary tumours. They are commonly multiple, gro...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1985
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)38842-7